Actively Recruiting
Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous
Led by Holy Family Hospital, Nazareth, Israel · Updated on 2026-04-13
142
Participants Needed
2
Research Sites
142 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomized controlled trial is to examine the efficacy of combining castor oil ingestion with extra-amniotic single balloon catheter for cervical ripening on time from induction to delivery in nulliparous women. The main question it aims to answer are: Does the addition of the use of castor oil to extra-amniotic single balloon reduce the time until birth? Does the addition of the castor oil affect other perinatal outcomes during childbirth? Are the side effects of the castor tolerated by the mothers? Participants will be randomly divided into 2 groups: the study group will drink a mixture of 60 ml of castor oil mixed with 140 ml of orange juice. Thirty minutes later, an extra-amniotic single balloon catheter will be inserted above the internal cervical os and filled with 60 mL of normal saline. In the control group, a foley catheter will be inserted into cervical canal without ingestion of castor oil.
CONDITIONS
Official Title
Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women above 18 years old
- Sign an informed consent
- Term pregnancy (>37 weeks)
- Viable fetus
- Singleton pregnancy
- Baby in vertex (head-down) position
- Intact membranes
- Cervix with Bishop score 6
You will not qualify if you...
- Previous cesarean delivery
- Major fetal malformations
- Contraindication to spontaneous vaginal delivery
- Amniotic fluid index >25cm
- Chorioamnionitis at admission
- Placental abruption
- Previous prostaglandin use for induction of labor
- Low-lying placenta (up to 2 cm from the internal os)
- Carriers of hepatitis B or C or HIV
- History of allergy to latex
- History of allergy to castor oil
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Holy Family hospital, Nazareth
Nazareth, Israel
Not Yet Recruiting
2
Holy Family Hospital
Nazareth, Israel
Actively Recruiting
Research Team
R
Raed Salim, MD
CONTACT
W
wiaam khatib, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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