Structure and neural mechanisms of catatonia.
Sebastian Walther, Katharina Stegmayer, Jo Ellen Wilson...
https://pubmed.ncbi.nlm.nih.gov/31196794/Actively Recruiting
Led by Beatriz Rodriguez Cabo · Updated on 2026-05-12
40
Participants Needed
1
Research Sites
260 weeks
Total Duration
Researchers are studying catatonic syndrome, a serious neuropsychiatric condition with motor, behavioral, and speech symptoms, in adults treated at Basurto University Hospital in Spain. The study aims to understand how often catatonia occurs, its patient characteristics, treatment responses, and short-term outcomes. This observational study will include all adult patients diagnosed with catatonia of any cause from January 2024 to December 2025, examining a broad hospital population across different clinical settings. The study does not involve experimental treatments but will collect detailed clinical data from patients diagnosed according to DSM-5 criteria. Severity and subtype of catatonia will be assessed using the Bush-Francis Catatonia Rating Scale, with patients followed through their hospital stay until discharge. Researchers will document treatments given during routine care, including benzodiazepines and other interventions, and monitor patients clinical progress and complications. Participants will have their demographic data, clinical features, underlying diagnoses, treatment responses, and hospital outcomes recorded. Data collection includes clinical assessments, rating scales, and tracking of hospital events such as complications and length of stay. The primary outcome is the annual incidence of catatonia in the hospital population. The study will also analyze secondary variables such as symptom severity, treatment effects, and short-term recovery patterns. Participation involves no extra procedures beyond standard care, and consent procedures accommodate acute illness situations.
CONDITIONS
Catatonic Syndrome in Adult Patients at Basurto Hospital: A Descriptive Study of Incidence, Comorbidity, and Short-Term Outcomes
B
Beatriz Rodriguez-Cabo, Professor
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Beatriz Rodriguez Cabo
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Screening and enrollment occur during hospital care when catatonia is diagnosed.
Duration - Duration of hospital stay from diagnosis until discharge
Participants diagnosed with catatonic syndrome are observed throughout their hospital stay to collect clinical data on incidence, characteristics, treatment response, and short-term outcomes.
Assessments occur during routine hospital visits as part of standard care
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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https://pubmed.ncbi.nlm.nih.gov/18851928/Beatriz Rodriguez Cabo
Lead Sponsor