Actively Recruiting

Phase 3
Age: 55Years +
All Genders
NCT05047198

Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial

Led by Ottawa Heart Institute Research Corporation · Updated on 2025-11-20

244

Participants Needed

1

Research Sites

262 weeks

Total Duration

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AI-Summary

What this Trial Is About

This study compares two arms - the current standard of care catheter ablation for Ventricular Tachycardia compared to stereotactic radiotherapy to non-invasively ablate ventricular tachycardia using a novel non-invasive ECG based body surface mapping technology. This allows investigators to identify ventricular tachycardia circuits to target for subsequent radio ablation. To summarize, the current standard of care invasive catheter ablation to the non-invasive radio ablation.

CONDITIONS

Official Title

Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial

Who Can Participate

Age: 55Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient aged 55 years or older
  • Cardiomyopathy with left ventricular ejection fraction 35% or less and ICD implanted
  • Recurrent ventricular tachycardia events despite previous catheter ablation OR ventricular tachycardia events requiring intervention with PAINESD score 15 or higher
Not Eligible

You will not qualify if you...

  • NYHA Class IV heart failure or left ventricular assist device in place
  • Life expectancy less than one year for any reason
  • Previous thoracic radiotherapy
  • Currently enrolled in another randomized clinical trial
  • Unable or unwilling to provide informed consent
  • Age under 55 years
  • Pregnancy
  • Breastfeeding
  • Women of childbearing age who do not agree to use effective contraception during the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Ottawa Heart Institute

Ottawa, Ontario, Canada, K1Y 4W7

Actively Recruiting

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Research Team

C

Calum Redpath

CONTACT

T

Tammy Knight

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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