Actively Recruiting
Causal Role of the Aperiodic Signal for Working Memory
Led by Florida State University · Updated on 2026-01-12
30
Participants Needed
1
Research Sites
140 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Working memory (WM) is the ability to hold relevant information in mind in the absence of sensory input. The capacity for WM is a foundation for cognitive control and higher cognitive function more broadly. Previous research demonstrated that during the delay period of WM tasks, oscillatory electrical activity in the prefrontal cortex in the theta-frequency band (4-8 Hz) increased in amplitude. However, other groups found that the slope of the aperiodic signal in the brain was positively correlated with individual differences in WM capacity. Since low-frequency power and a steeper slope of the aperiodic signal are confounded in many analyses, it is not clear whether the slope of the aperiodic signal or the amplitude of low-frequency oscillations underlie WM capacity. With many studies investigating the causal role of theta oscillations in WM, the purpose of this project is to investigate the role of the aperiodic signal in WM performance.
CONDITIONS
Official Title
Causal Role of the Aperiodic Signal for Working Memory
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between the ages of 18 and 35
- Able to provide informed consent
- Normal or corrected-to-normal vision
- Willing to comply with all study procedures and be available for the duration of the study
- Ability to speak, read and understand English without a translator
- Not color-blind
You will not qualify if you...
- Currently being treated for ADHD or ADD
- Presence of neurological disorders or conditions
- Medical or neurological illness or treatment that could interfere with participation, such as unstable cardiac disease, HIV/AIDS, malignancy, liver or kidney impairment
- Prior brain surgery
- Any brain devices or implants, including cochlear implants and aneurysm clips
- History of traumatic brain injury
- Pregnant females
- Any condition that may increase risk or prevent full compliance as judged by the investigator
- Current use of medications that affect EEG activity, including benzodiazepines, antipsychotics, antiepileptics, and central nervous system stimulants
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Florida State University
Tallahassee, Florida, United States, 32306
Actively Recruiting
Research Team
J
Justin Riddle, PhD
CONTACT
L
Lauren Jackson, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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