Comparing Cauterization and Fibrin Glue for Conjunctival Autografting in Primary Pterygium Surgery A Study on Treatment Effects in Adults with Pterygium

What this Trial Is About

Pterygium is a noncancerous growth of the conjunctival tissue over the cornea that can progress to cause vision problems, eye movement restrictions, chronic inflammation, and cosmetic issues. This clinical trial evaluates and compares two methods for securing conjunctival autografts during primary pterygium surgery cauterization and fibrin glue. The study is randomized and controlled to assess which method may influence recurrence rates and other outcomes. The two interventions studied are cauterization, where a bipolar cutter is used to secure the graft with controlled cauterizing wraps, and fibrin glue, where a fiber adhesive is prepared and applied to fix the graft. The fibrin glue preparation takes about 10 to 15 minutes and is performed by a nurse. Both procedures aim to secure the conjunctival autograft during surgery to prevent recurrence. Participants will be followed for 180 days after surgery to monitor the recurrence of pterygium, surgical time, complication rates, astigmatism caused by pterygium, ocular surface condition, and postoperative symptoms such as discomfort, tearing, pain, and foreign body sensation. Pain and economic analyses will also be assessed at various time points including 7, 30, and 180 days after surgery. The study includes triple masking and random allocation to study groups.

Cauterization Versus fibrin Glue for Conjunctival Autografting in Primary Pterygium Surgery