Actively Recruiting

Age: 0Years - 21Years
All Genders
NCT07246213

CAYA Cancer Retrospective Cohort Study

Led by Resonance, Inc. · Updated on 2025-12-19

18000

Participants Needed

5

Research Sites

182 weeks

Total Duration

On this page

Sponsors

R

Resonance, Inc.

Lead Sponsor

S

Servier Affaires Médicales

Collaborating Sponsor

AI-Summary

What this Trial Is About

Despite advances in cancer treatment, significant disparities in outcomes persist between high-income countries (HICs) and low-and middle-income countries (LMICs). Around 80% of children with cancer live in LMICs, where they face challenges such as delayed diagnosis, misdiagnosis, comorbidities, distance to treatment, financial barriers, and limited access to risk-adapted therapies. Acute lymphoblastic leukemia(ALL)/lymphoblastic lymphoma(LBL), for example, is one of the greatest success stories in pediatric oncology, however, such improvements are not evenly distributed worldwide, and the outcomes for leukemia patients are poorer in LMICs compared to HICs, primarily due to reduced access to quality healthcare. This study aims to assess cancer treatment outcomes in LMICs, focusing on acute lymphoblastic leukemia/lymphoblastic lymphoma. The findings will inform future studies to implement evidence-based interventions that improve care quality and reduce treatment failures through targeted strategies.

CONDITIONS

Official Title

CAYA Cancer Retrospective Cohort Study

Who Can Participate

Age: 0Years - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be willing and able to provide informed consent before enrollment, or assent with guardian consent for minors or those unable to consent.
  • Diagnosed with any type of cancer within 15 years prior to the site's activation date.
  • Aged from 0 to 21 years at the time of diagnosis.
  • Received substantial anti-cancer treatment at the participating center, including chemotherapy, surgery, radiation therapy, or immunotherapy.
  • Medical records must be available and accessible for review.
Not Eligible

You will not qualify if you...

  • Patients who only visited the participating center for consultation without receiving primary anti-cancer treatment there.
  • Patients who only had pathology, radiology, or other diagnostic evaluations without treatment at the participating center.

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 5 locations

1

Yeolyan Center for Cancer and Blood Disorders

Yerevan, Armenia

Actively Recruiting

2

Fundación Ayúdame a Vivir

El Salvador, El Salvador, El Salvador, 1101

Not Yet Recruiting

3

Unidad Nacional de Oncología Pediátrica (UNOP)

Guatemala City, Guatemala

Actively Recruiting

4

Hospital Mario Catarino Rivas

San Pedro Sula, Cortés Department, Honduras, 21102

Not Yet Recruiting

5

Hospital Escuela

Tegucigalpa, Distrito Central, Honduras, 11101

Not Yet Recruiting

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Research Team

G

Gabriela Villanueva, MD.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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CAYA Cancer Retrospective Cohort Study | DecenTrialz