Actively Recruiting

Phase Not Applicable
Age: 13Years - 17Years
All Genders
NCT05456035

CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth

Led by Vanderbilt University · Updated on 2025-09-09

82

Participants Needed

1

Research Sites

198 weeks

Total Duration

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Sponsors

V

Vanderbilt University

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth between ages 13- through 17-years-old currently experiencing depression. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind (CBTSCT) as compared to CBT only. The primary target is improvement in both social cognitive skills and depressive symptoms at post-treatment and at a 6-month follow-up.

CONDITIONS

Official Title

CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth

Who Can Participate

Age: 13Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants ages 13 through 17 years old
  • Diagnosis of current depressive disorder or a Patient Health Questionnaire (PHQ9) score greater than 15
Not Eligible

You will not qualify if you...

  • History of bipolar disorder, schizophrenia, autism, or conduct disorder
  • Current alcohol or substance use disorder with significant impairment
  • Imminent risk of suicide
  • Reading level below 4th grade

AI-Screening

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Trial Site Locations

Total: 1 location

1

Judy Garber

Nashville, Tennessee, United States, 37203-5721

Actively Recruiting

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Research Team

J

Judy Garber, PhD

CONTACT

S

Steven D Hollon, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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