Actively Recruiting

Phase Not Applicable
Age: 6Years - 14Years
All Genders
NCT05031364

CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings

Led by University of California, Los Angeles · Updated on 2026-02-09

100

Participants Needed

3

Research Sites

260 weeks

Total Duration

On this page

Sponsors

U

University of California, Los Angeles

Lead Sponsor

V

Virginia Commonwealth University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is a 4-year randomized, controlled trial comparing cognitive behavioral therapy (CBT) to usual clinical care for children (aged 6-14 years) with autism and emotional dysregulation (e.g., irritability, anxiety). We will randomly assign 50 mental health clinicians, each treating 2 youth (N = 100 youth total), to CBT program for emotional dysregulation and core autism symptoms with weekly live consultation with an expert or to usual clinical care augmented by self-instruction in CBT, in a 1:1 allocation. The CBT manual is well-supported in our efficacy research, has been replicated in other centers, is free/open-access (meya.ucla.edu), and has user-friendly digital and traditional print materials for mental health clinicians (e.g., psychologists, counselors) to use in preparing for and conducting therapy sessions. The primary outcome measure will be assessed weekly. Additional assessments will occur at Screening, Mid-treatment, Post- treatment and 3-month Follow-up.

CONDITIONS

Official Title

CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings

Who Can Participate

Age: 6Years - 14Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Youth aged 6 to 14 years
  • Boys or girls with a clinical diagnosis of autism spectrum disorder confirmed by a licensed professional
  • Parent-reported Social Responsive Scale-2 (SRS-2) Total T-Score above 60
  • Clinically significant emotional dysregulation symptoms with Brief Problem Monitor (BPM) T-scores of at least 60 on Externalizing or Internalizing subscales and a minimum 15-point difference between these subscales
  • Vineland Adaptive Behavior Scales-3 Communication Composite Standard Score above 60 and Expressive Communication subscale v-score above 8
  • Newly referred for outpatient services with a participating clinician
  • Clinicians must treat youth with ASD regularly and agree to enroll at least 2 families in the study per clinician
Not Eligible

You will not qualify if you...

  • Severe comorbid symptoms such as psychotic symptoms that require immediate treatment or ongoing medication adjustments

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Westside Regional Center

Culver City, California, United States, 90024

Actively Recruiting

2

California Autism Professional Training and Information Network (CAPTAIN)

Sacramento, California, United States, 95817

Actively Recruiting

3

Naval Medical Center San Diego

San Diego, California, United States, 92115

Actively Recruiting

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Research Team

W

Wood

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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