Actively Recruiting
Chest Compression Synchronized Ventilation (CCSV) - an Exploratory Post Market Clinical Follow-up Study
Led by Medical University of Vienna · Updated on 2025-02-20
98
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
Sponsors
M
Medical University of Vienna
Lead Sponsor
W
WEINMANN Emergency, Medical Technology GmbH & Co. KG
Collaborating Sponsor
AI-Summary
What this Trial Is About
This observational study evaluates Chest Compression Synchronized Ventilation (CCSV) compared to Intermittent Positive Pressure Ventilation (IPPV) in patients who experience cardiac arrest. The focus is on oxygen levels measured by blood gas analysis, hemodynamic effects, 30-day patient outcomes, and safety. There is limited human data on CCSV, especially in direct comparison with other ventilation methods, which this study aims to address. Cardiac arrest patients in Vienna will be randomly assigned before hospital arrival to receive either IPPV or CCSV ventilation during cardiopulmonary resuscitation (CPR). Ventilation is performed using the MEDUMAT Standard device from Weinmann Emergency, following specific mechanical ventilation guidelines. The study groups include patients ventilated with IPPV and those ventilated with CCSV. Participants will be monitored for oxygenation, carbon dioxide removal, systemic blood flow, and brain oxygen levels during CPR. Researchers will also track patients' outcomes after 30 days and observe any ventilator-related complications like pneumothorax. Data collection will continue for up to 27 months to assess both short- and longer-term effects of the ventilation methods.
CONDITIONS
Brief Title
CCSV - Post Market Clinical Follow-up Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Out-of-hospital cardiac arrest (OHCA)
- Correct endotracheal intubation confirmed by capnography
- Patient treated by Vienna Emergency Medical Services for emergency ventilation
- Use of MEDUMAT Standard ventilator from Weinmann Emergency
- Mechanical ventilation performed according to specified indications
You will not qualify if you...
- Patients eligible for extracorporeal CPR (eCPR) per Vienna Emergency Medical Service protocol
- Patients who regain spontaneous circulation before or within first three minutes of mechanical ventilation
- Any other mechanical ventilation during ongoing CPR before study inclusion
- Traumatic cardiac arrest
- Suspected or known pregnancy
- Clinically suspected tension pneumothorax
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 27 months
Participants who undergo routine care are observed to assess oxygenation, decarboxylation, systemic perfusion, patient outcomes, and ventilator-associated adverse events.
Trial Site Locations
Total: 1 location
1
Medical University of Vienna
Vienna, Austria, Austria, 1090
Actively Recruiting
Research Team
S
Sebastian Schnaubelt, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here