Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06569082

CD34+ Selected Stem Cell for Poor Graft Function or Graft Failure

Led by NYU Langone Health · Updated on 2025-09-29

21

Participants Needed

1

Research Sites

560 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The proposed trial is a single arm, non-randomized, single center pilot study utilizing CliniMACS CD34 Reagent System for patients following allogeneic hematopoietic stem cell transplant (HSCT) requiring treatment of graft dysfunction or failure.

CONDITIONS

Official Title

CD34+ Selected Stem Cell for Poor Graft Function or Graft Failure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult recipients (18 years and older) of allogeneic stem cell transplant from any donor type
  • Documented graft dysfunction or failure including primary graft failure, poor graft function, or secondary graft failure
  • Donor available to provide peripheral blood stem cells
  • Negative pregnancy test within 7 days of infusion for women of childbearing potential
Not Eligible

You will not qualify if you...

  • Graft failure caused by disease relapse or disease progression
  • Donor unavailable or unable to provide peripheral blood stem cells by apheresis
  • Responding to conventional treatments such as hematopoietic growth factors
  • Allergic reaction to murine proteins or iron dextran
  • Women of childbearing potential with positive serum HCG

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

NYU Langone Health

New York, New York, United States, 10016

Actively Recruiting

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Research Team

K

Kiselle Mangalindan

CONTACT

K

Kelsey Stocker

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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