Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT07265271

A Cell-free tsRNA Signature for Early Detection of Hepatocellular Carcinoma

Led by City of Hope Medical Center · Updated on 2025-12-10

600

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Hepatocellular carcinoma (HCC) is often diagnosed at an advanced stage, and early detection is critical for improving patient outcomes. Despite this, reliable non-invasive biomarkers for early-stage HCC are limited. This study seeks to develop a cell-free tsRNA (cf-tsRNA)-based liquid biopsy assay for accurate detection of early-stage HCC.

CONDITIONS

Official Title

A Cell-free tsRNA Signature for Early Detection of Hepatocellular Carcinoma

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • A histologically confirmed diagnosis of hepatocellular carcinoma.
  • Received standard diagnostic and staging procedures as per local guidelines
  • Availability of at least one blood-derived sample, drawn before receiving any curative-intent treatment
Not Eligible

You will not qualify if you...

  • Lack of or inability to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

City of Hope Medical Center

Duarte, California, United States, 91016

Actively Recruiting

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Research Team

G

Goel Ajay, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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