Actively Recruiting
Cellulitis Optimal Antibiotic Treatment
Led by University of Southampton · Updated on 2024-12-09
356
Participants Needed
1
Research Sites
161 weeks
Total Duration
On this page
Sponsors
U
University of Southampton
Lead Sponsor
U
University of East Anglia
Collaborating Sponsor
AI-Summary
What this Trial Is About
To determine whether a short course of oral flucloxacillin (5 days) is non-inferior to a standard course (7 days) in terms of pain over days 6-14 (indicative of persistence or recurrence associated with the symptoms of most importance to patients) in adults with cellulitis of the leg presenting in primary care.
CONDITIONS
Official Title
Cellulitis Optimal Antibiotic Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Must be aged 18 years or older
- Currently showing symptoms of cellulitis in one leg for 10 days or less
- Pain rated as 3/10 or higher at baseline assessment
- Willing to be randomized to either 5-day or 7-day treatment
- Able to complete trial procedures in English
You will not qualify if you...
- Have penicillin allergy
- Have cellulitis in both legs
- Had antibiotics for cellulitis within the past month
- Have post-operative cellulitis within 30 days on the same leg
- Cellulitis caused by human or animal bite
- Cellulitis linked to chronic leg ulceration lasting more than 6 weeks
- Need immediate hospital admission or intravenous antibiotics
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Royal South Hants Hospital
Southampton, United Kingdom
Actively Recruiting
Research Team
S
Sophie Varkonyi-Clifford
CONTACT
E
Ella Bourke
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here