Actively Recruiting
Central-boost Ablative Radiation Therapy for Solid Tumors (CBART)
Led by Changhai Hospital · Updated on 2024-05-23
67
Participants Needed
1
Research Sites
137 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In the case of large tumors or tumors closely adjacent to organs at risk, ablative doses offered by stereotactic body radiation therapy (SBRT) could not be delivered. Therefore, a technique that could provide high radiation doses to tumors without increasing of risks of severe adverse effects is required.
CONDITIONS
Official Title
Central-boost Ablative Radiation Therapy for Solid Tumors (CBART)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18-75 years
- Pathologically confirmed lung, liver, pancreas, or retroperitoneal malignant tumor
- Oligometastasis if the tumor is metastatic
- Tumor shortest diameter of at least 2 cm or tumor located less than 5 mm from organs at risk
- ECOG performance status of 0 to 1
- Normal blood routine, liver and kidney function, and coagulation tests (white blood cell count 24.0�d7 10^9/L, neutrophil count 2.0�d7 10^9/L, hemoglobin 100 g/L, platelet count 100�d7 10^9/L, ALT and AST < 2.5 times upper normal limit, normal bilirubin and creatinine, INR < 2)
You will not qualify if you...
- Previous radiotherapy to the lesion
- History of tumor within the past 5 years
- ECOG performance status of 2 or higher
- Significant abnormalities in blood routine, liver or kidney function, or coagulation tests
- Active inflammatory bowel disease for pancreas or retroperitoneal tumors
- Gastrointestinal bleeding or perforation within 6 months for pancreas or retroperitoneal tumors
- Current infections requiring antibiotics
- Heart or respiratory failure
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Huojun Zhang
Shanghai, Shanghai Municipality, China, 200433
Actively Recruiting
Research Team
X
Xiaofei Zhu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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