Randomized Comparison of Two Ultrasound-Guided Techniques for Central Venous Catheter Placement in Emergency Care

What this Trial Is About

Researchers are comparing two different methods for placing central venous catheters CVCs in adult patients needing ultrasound-guided central line placement in emergency settings. The study aims to see if using a peripheral intravenous catheter technique leads to higher first attempt success rates, fewer complications, and quicker procedure times compared to the traditional wire-through-hollow bore needle method. This comparison is important because the newer technique allows continuous use of ultrasound during catheter placement and may reduce vessel damage. Participants will be randomly assigned to receive central venous access either by the standard hollow bore needle with a wire or by a peripheral intravenous catheter. Both methods use ultrasound guidance to locate the veins. The peripheral IV catheter method requires only one hand, potentially making the procedure easier and safer by maintaining ultrasound visualization throughout. The study involves direct clinical procedures performed by physicians and compares timing and success outcomes within the first 20 minutes of the procedure. During the study, participants will undergo central venous catheter insertion using the assigned technique, and researchers will observe and record outcomes such as number of attempts, time to complete the procedure, and any adverse events. The primary outcome is successful catheter placement on the first attempt within 20 minutes. Secondary outcomes include overall success, number of guidewire passages, procedure duration, and complications. The trial is randomized and triple-blinded, with data collected to assess effectiveness and safety of each method until study completion in December 2027.

Central Line Study