Actively Recruiting
Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study
Led by University of California, San Francisco · Updated on 2026-04-29
80
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is being conducted to assess two imaging methods-central microperimetry and radial OCT (Optical Coherence Tomography)-in patients with Geographic Atrophy (GA) or those who are at risk of developing this condition. The study team is trying to determine whether these methods can provide more accurate measurements of GA progression toward the foveal center, the central part of the retina responsible for your sharpest, most detailed vision.
CONDITIONS
Official Title
Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects must be 55 years of age or older
- Subjects in the Intermediate AMD Observation Arm must have intermediate age-related macular degeneration in one eye
- Subjects in the GA Observation Arm, GA Continuing Treatment Arm, and GA Treatment Arm must have non-central geographic atrophy with at least 1% GA in the central 1 mm zone
You will not qualify if you...
- Subjects with central involvement of geographic atrophy affecting the foveal center point
- Subjects with baseline GA size larger than 17.5 mm2 (7.0 Macular Photocoagulation Study Disc Areas)
- Pregnant women, adults unable to consent for themselves, and those with excessive alcohol use (binge drinking 5 or more days in the past month)
- Evidence of retinal atrophy from causes other than atrophic AMD
- Anti-VEGF injections or active choroidal neovascularization in the study eye within the last 12 months
- Ocular disorders in the study eye that may affect outcomes including severe diabetic retinopathy, retinal vein or artery occlusion, macular hole, pathologic myopia, uveitis, pseudovitelliform maculopathy
- Intraoperative surgery within 90 days before study enrollment in the study eye
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
Research Team
J
Jay M Stewart, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here