Actively Recruiting
Central Motor Mechanisms in AIS Via HD-sEMG, EEG and Neuromuscular Coupling Analysis
Led by The First Affiliated Hospital of Zhejiang Chinese Medical University · Updated on 2025-01-03
40
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
1. Verifying the Motor Control Effects of Spinal Manipulation on AIS Using outpatient and inpatient AIS patients from our department as the study subjects, standardized spinal manipulation treatment is applied. The efficacy is evaluated through a combination of clinical outcome measures, HD-EMG for paraspinal muscle function assessment, and Pro-Kin balance system for trunk stability analysis. This establishes an AIS efficacy platform to further clarify the effectiveness of spinal manipulation in motor control regulation of AIS. 2. Investigating the Central Motor Network's Response to Spinal Manipulation in AIS Utilizing high-density sEMG-EEG technology, synchronized brain and muscle electrical signals are collected before and after treatment. By employing a neuromuscular synchronization and coupling analysis approach that integrates linear and nonlinear methods, the characteristic indices of information interaction between the central system and muscles are identified. This further explores the motor control and response characteristics of the muscle-cortex network to spinal manipulation in AIS.
CONDITIONS
Official Title
Central Motor Mechanisms in AIS Via HD-sEMG, EEG and Neuromuscular Coupling Analysis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 10 years and older
- Risser sign grade 0 to 3
- Cobb angle between 10° and 40°
- No prior treatment for scoliosis
- Female patients within 1 year after menarche or before menstruation
- Patient's guardian has signed informed consent form for treatment
You will not qualify if you...
- Not meeting the diagnostic criteria for AIS or the inclusion criteria
- Severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, or hematopoietic disorders, or mental illnesses
- Thrombocytopenia, coagulation disorders, or bleeding tendency
- Fear of treatment and inability to tolerate it
- Previous treatments that may affect study outcome measures
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
the First Affiliated Hospital of Zhejiang Chinese Medical University
Hangzhou, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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