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Study of Motor Control and Brain-Muscle Interaction in Adolescents with Idiopathic Scoliosis Using HD-sEMG, EEG, and Neuromuscular Analysis
Led by The First Affiliated Hospital of Zhejiang Chinese Medical University · Updated on 2025-01-03
40
Participants Needed
1
Research Sites
78 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying the central motor regulation mechanism in patients with Adolescent Idiopathic Scoliosis AIS aged 10 to 18 years. They aim to understand how spinal manipulation affects motor control by evaluating muscle function and trunk stability using clinical outcome measures, high-density electromyography HD-EMG, and the Pro-Kin balance system. The study also investigates how the central motor network responds to spinal manipulation by analyzing synchronized brain and muscle electrical signals with advanced neuromuscular synchronization and coupling methods. Participants receive standardized spinal manipulation treatment called Tuina Massage Therapy, which involves correcting abnormal joint alignment, muscle function, and restoring joint stability and sensorimotor control. The therapy lasts 20-25 minutes per session and is applied twice a week for 12 weeks. The study compares AIS patients to a healthy control group to clarify the effectiveness of spinal manipulation on motor control in AIS. Throughout the study, participants will undergo evaluations before treatment and at 4 and 12 weeks after treatment using HD-EMG and the Pro-Kin balance system to assess paraspinal muscle function and trunk stability. Researchers analyze brain and muscle electrical signals to understand motor control characteristics. The study includes monitoring of clinical outcomes and motor network response, with total participation lasting at least 12 weeks and follow-up assessments at specified intervals.
CONDITIONS
Brief Title
Central Motor Mechanisms in AIS Via HD-sEMG, EEG and Neuromuscular Coupling Analysis
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