Actively Recruiting
Cerclage With Progesterone Versus Progesterone Only in Singleton Pregnancies
Led by Mỹ Đức Hospital · Updated on 2025-09-16
328
Participants Needed
1
Research Sites
118 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study compares the effectiveness of cervical cerclage with vaginal progesterone to vaginal progesterone only for the prevention of preterm birth in women with a singleton pregnancy and a short cervical length. Participants will be randomly assigned in a 1:1 ratio to receive cerclage plus progesterone or progesterone only.
CONDITIONS
Official Title
Cerclage With Progesterone Versus Progesterone Only in Singleton Pregnancies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Maternal age 18 years or older
- Singleton pregnancy
- Cervical length 25 mm or less measured by transvaginal ultrasound between 16 0/7 and 24 0/7 weeks of gestation
- Not participating in any other maternity or fetal intervention study
- Written informed consent provided by signing the consent form
You will not qualify if you...
- Cervical dilation with visible amniotic membranes or membranes prolapsed into the vagina
- Major congenital abnormalities of the fetus
- Intrauterine fetal death
- Severe vaginal discharge
- Vaginitis or cervicitis
- Vaginal bleeding
- Placenta previa or vasa previa
- Preterm premature rupture of membranes
- Preterm labor without ruptured membranes at screening
- Suspected chorioamnionitis
- Unable to undergo cerclage procedure
- Existing cerclage in place
- Allergy to progesterone
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
My Duc Hospital
Ho Chi Minh City, Ho Chi Minh City, Vietnam, 70000
Actively Recruiting
Research Team
T
Thanh V Le, MD
CONTACT
L
Lan N Vuong, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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