Actively Recruiting
Cerebellar Stimulation for Aphasia Rehabilitation
Led by Johns Hopkins University · Updated on 2026-03-20
60
Participants Needed
1
Research Sites
335 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
N
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The optimal site of neuromodulation for post-stroke aphasia has yet to be established. This study will investigate whether multiple sessions of cerebellar transcranial direct current stimulation (tDCS) boosts language therapy in helping people recover from aphasia as well as predict who is likely to respond to cerebellar tDCS.
CONDITIONS
Official Title
Cerebellar Stimulation for Aphasia Rehabilitation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chronic ischemic or hemorrhagic left hemisphere stroke
- Fluent speaker of English by self-report
- Age 18 or older
- At least 6 months after stroke onset
- Diagnosis of aphasia with naming impairment confirmed by the Western Aphasia Battery-Revised
You will not qualify if you...
- Lesion in the right cerebellum
- Previous neurological disorder (other than stroke), neurodegenerative disorder, or psychiatric disorder
- Seizures in the past 6 months
- Uncorrected vision or hearing loss by self-report
- Use of medications that lower seizure threshold (e.g., methylphenidate)
- Use of NMDA antagonists (e.g., memantine)
- History of brain surgery or metal in the head
- Severely impaired auditory comprehension (score lower than 2 on the Western Aphasia Battery-Revised)
- Severely limited verbal output (score lower than 2 on the Spontaneous Speech rating scale of the Western Aphasia Battery-Revised)
- Severe claustrophobia, cardiac pacemakers, ferromagnetic implants, or pregnancy (excluded from MRI portion)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Johns Hopkins Hospital
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
R
Rajani Sebastian, PhD
CONTACT
B
Becky Lammers, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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