Actively Recruiting

Phase Not Applicable
Age: 18Years - 64Years
All Genders
NCT05938543

Cerebellar TMS and Satiety in Prader-Willi Syndrome

Led by Brigham and Women's Hospital · Updated on 2025-12-05

20

Participants Needed

1

Research Sites

160 weeks

Total Duration

On this page

Sponsors

B

Brigham and Women's Hospital

Lead Sponsor

F

Foundation for Prader-Willi Research

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study hyperphagia and satiety in Prader-Willi syndrome. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about how TMS might improve hyperphagia in Prader-Willi syndrome.

CONDITIONS

Official Title

Cerebellar TMS and Satiety in Prader-Willi Syndrome

Who Can Participate

Age: 18Years - 64Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Prader-Willi syndrome
Not Eligible

You will not qualify if you...

  • Contraindications for TMS or MRI including:
  • History of neurological disorder
  • History of head trauma resulting in loss of consciousness
  • History of seizures or diagnosis of epilepsy or first degree relative family history of epilepsy
  • Metal in brain or skull
  • Implanted devices such as a pacemaker, medication pump, nerve stimulator or ventriculoperitoneal shunt
  • Claustrophobic in MRI

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

McLean Hospital

Belmont, Massachusetts, United States, 02478

Actively Recruiting

Loading map...

Research Team

L

Laura Holsen, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Cerebellar TMS and Satiety in Prader-Willi Syndrome | DecenTrialz