Actively Recruiting
Cerebello-motor Neuromodulation After Stroke. CERSTIM.
Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2026-04-16
45
Participants Needed
2
Research Sites
158 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The CERSTIM study is a physiopatholgical study investigating transcranial alternating current stimulation in stroke patients in the cerebello-motor loop. The design is a cross over design testing two frequencies in the gamma band and one placebo. We will use behavioural data, functional MRI, and Electroencephalography to disentangle the effect of tACS and its frequency. Healthy participants will be also recruited.
CONDITIONS
Official Title
Cerebello-motor Neuromodulation After Stroke. CERSTIM.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female aged 18 years or older on the day of inclusion
- Affiliated with a social security system, Universal Health Coverage (CMU), or equivalent
- For patients: ischemic stroke or intraparenchymal hematoma more than 6 months ago
- For patients: motor deficit of the upper limb confirmed by ARAT scale with ability to grip and press on a tablet
- Stroke lesion not affecting the motor cortex in the hand knob area
- For healthy participants: male or female aged 18 years or older on the day of inclusion
- For healthy participants: affiliated with a social security system, Universal Health Coverage (CMU), or equivalent
You will not qualify if you...
- Pregnant and breastfeeding women
- Total paralysis of the affected hand
- Life-threatening conditions or those that could compromise study follow-up
- Contraindications to MRI and tACS such as ferromagnetic surgical clips, ocular implants, metallic foreign bodies, cochlear implants, brain or cardiac stimulators, or craniotomy scar
- Participation in another biomedical study focused on motor or overall recovery during the same period or current exclusion period from another biomedical study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
ICM_ Institut du Cerveau et de la Moelle épinière, Hôpital Pitié, 47 Bd de l'Hôpital
Paris, France, 75013
Actively Recruiting
2
ToNIC - Toulouse neuro Imaging center (Inserm)Pavillon Baudot
Toulouse, France, 31300
Not Yet Recruiting
Research Team
C
Charlotte ROSSO, MD PhD
CONTACT
I
Isabelle LOUBINOUX, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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