Actively Recruiting
Cerebral Autoregulation in Patients With Symptomatic Cerebral Atherosclerotic Stenosis
Led by Yi Yang · Updated on 2024-03-01
850
Participants Needed
1
Research Sites
502 weeks
Total Duration
On this page
Sponsors
Y
Yi Yang
Lead Sponsor
S
Shenzhen Second People's Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this multi-center prospective observational study within a cohort of symptomatic cerebral atherosclerotic stenosis (sCAS) patients, 850 subjects were planed to be enrolled to explore the relationship between cerebral autoregulation (CA) and stroke recurrence, determine the threshold values of CA parameter for predicting stroke recurrence associated with particular stenosis.
CONDITIONS
Official Title
Cerebral Autoregulation in Patients With Symptomatic Cerebral Atherosclerotic Stenosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years, any gender
- Unilateral stenosis of internal carotid artery or middle cerebral artery (50-99%)
- Recent ischemic stroke or transient ischemic attack in the area supplied by the stenotic artery
- Stroke or TIA onset less than 30 days before enrollment
- Modified Ranking Scale score of 1 or less before the stroke
- National Institutes of Health Stroke Scale score 20 or less
- Adequate temporal bone windows on both sides for ultrasound
- Conscious and able to cooperate with cerebral autoregulation tests
- Willing to participate and provide informed consent
You will not qualify if you...
- Stenosis in vertebral, basilar, anterior cerebral, or posterior cerebral arteries, or bilateral stenosis of internal carotid or middle cerebral arteries (50-99%)
- Patients who have had or plan to have intravascular intervention or endarterectomy
- Other brain diseases such as cerebral hemorrhage, brain tumors, aneurysms, or arteriovenous malformations
- Causes of embolic stroke like atrial fibrillation, prosthetic heart valve, or suspected endocarditis
- Arrhythmia, anemia, or hyperthyroidism affecting cerebral blood flow stability
- Dementia, severe anxiety, depression, or other mental illnesses
- Malignant tumors with life expectancy under 2 years
- Participation in other clinical trials within the last 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
the First Hospital of Jilin University
Changchun, Jilin, China, 130000
Actively Recruiting
Research Team
Y
Yi Yang, MD, PhD
CONTACT
Z
Zhenni Guo, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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