Actively Recruiting
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Led by University of Calgary · Updated on 2026-05-01
12
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).
CONDITIONS
Official Title
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy adults
- Aged 18 to 45 years
- Living in Calgary for the past one year
- No medical conditions and not taking blood pressure medications
- Not lactose intolerant
You will not qualify if you...
- History of cerebrovascular, cardio-respiratory, kidney, or metabolic diseases
- Bleeding disorders or upper gastrointestinal diseases such as peptic ulcer disease
- Pregnancy, obesity, or sleep-disordered breathing
- Allergies to non-steroidal anti-inflammatory drugs
- Current smokers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Calgary
Calgary, Alberta, Canada, T2N 4N1
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
4
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