Brain Oxygen Use During Surgery and Risk of Delirium in Older Adults A Study Using Non-Invasive Forehead Monitoring In Patients 65 Years and Older Undergoing Laparoscopic Surgery

What this Trial Is About

This observational study focuses on adults aged 65 years and older who are undergoing elective laparoscopic surgery under general anesthesia. Researchers aim to understand if the brains ability to use oxygen during surgery is linked to the risk of developing postoperative delirium. The study evaluates whether reduced cerebral oxygen consumption responsiveness during surgery increases the chance of delirium after the operation. During surgery, participants will have their brain oxygen levels monitored using a non-invasive forehead sensor based on functional near-infrared spectroscopy technology. Oxygen levels in the anesthesia may be temporarily adjusted within routine clinical ranges to assess the brains response. No experimental oxygen or extra treatments will be given beyond standard care. After surgery, participants will be observed for up to three days to check for signs of delirium. Participants will undergo brain oxygen measurements during surgery and be assessed for delirium through clinical evaluations in the days following surgery. Researchers will track the occurrence of postoperative delirium as the primary outcome and measure cerebral oxygen utilization response during surgery as a secondary outcome. The total participation involves the surgery day and a three-day postoperative monitoring period to gather necessary data for the study.

Cerebral Oxygen Consumption Response to Increased Oxygen Supply and Postoperative Delirium in Older Surgical Patients