Actively Recruiting

Phase Not Applicable
Age: 19Years - 90Years
All Genders
NCT04421573

Cervical Plexus Hydrodissection With D5W for PTSD

Led by Dr. Dean Reeves Clinic · Updated on 2026-01-27

24

Participants Needed

4

Research Sites

220 weeks

Total Duration

On this page

Sponsors

D

Dr. Dean Reeves Clinic

Lead Sponsor

P

Paul Johnson, D.O.

Collaborating Sponsor

AI-Summary

What this Trial Is About

PTSD is a chronic mental health condition that drastically reduces an individual's quality of life Dextrose injection with a small needle has been used for chronic pain patients and observational results have shown it to be effective in reducing anxiety, brain fog, and depression in patients with PTSD. This randomized trial will compare dextrose injection with a delayed/usual treatment control.

CONDITIONS

Official Title

Cervical Plexus Hydrodissection With D5W for PTSD

Who Can Participate

Age: 19Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Not involved in another study of PTSD treatment
  • Reliable transportation
  • Comfortable with computers
  • Tried 2 or more medications for treatment of PTSD symptoms
  • Tried 2 or more non-medication treatments for PTSD symptom
  • No known life-threatening illness
  • Not taking daily narcotics
  • Not having 3 or more alcoholic drinks on an average day
  • No active suicidal plans
  • No major surgery plans
  • No major life stress that might interfere with completing study
  • Symptoms for more than 1 year
  • Not planning to move for next 18 months
  • Living within an hour of Portland, OR, Madison, WI, or Lexington, KY
  • Willing to provide 2 email and 2 phone contact methods
  • Willing to answer questions on multiple occasions over the course of a year
  • Willing to be assigned to 3 months of usual care treatment
  • No diagnosis of schizophrenia, Borderline Personality Disorder, or Bipolar Disorder
  • No severe needle phobia
  • Chronic pain 4/10
  • PCL-C score 50
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 4 locations

1

Danesh Mazloomdoost

Lexington, Kentucky, United States, 40509

Actively Recruiting

2

Paul W. Johnson, D.O., Clinic.

Portland, Oregon, United States, 87213

Actively Recruiting

3

NW Regen

Tigard, Oregon, United States, 97224

Actively Recruiting

4

Eric Phillippi M.D. Clinic

Madison, Wisconsin, United States, 53719

Actively Recruiting

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Research Team

K

Kenneth D Reeves, M.D.

CONTACT

K

Kenneth D Reeves, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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