Actively Recruiting
Change of Hemodynamics and Cerebral Functions After Carotid Artery Revascularization
Led by Beijing Friendship Hospital · Updated on 2022-09-14
200
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The majority (\>80%) of strokes are of ischemic etiology, of which ≈15% to 20% are attributable to atherosclerosis of the extracranial carotid arteries. The primary goal in carotid artery revascularization is to prevent stroke in patients with carotid artery stenosis. Treatment options including carotid endarterectomy (CEA) and carotid artery stenting (CAS). Hence, the investigators aim to compare carotid artery stenting (CAS) with carotid endarterectomy (CEA) in terms of long-term prognostic endpoints. Also, CEA and CAS result in different postoperative geometric features of carotid arteries that entail relevant modifications of rheological parameters, that may be associated with the risk of local complications and carotid artery restenosis. Finally, long-term and sustained cognitive benefits after carotid artery revascularization need further research and evidence.
CONDITIONS
Official Title
Change of Hemodynamics and Cerebral Functions After Carotid Artery Revascularization
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent
- Patients with 70% or greater symptomatic internal carotid stenosis
- Patients with 80% or greater asymptomatic internal carotid stenosis
You will not qualify if you...
- Unable to give informed consent
- Previous disabling stroke
- Contralateral carotid occlusion or greater than 70% stenosis
- Systemic disease incompatible with procedures or randomization
- Suspected or confirmed pregnancy
- General contraindications to MRI or CT studies
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100050
Actively Recruiting
Research Team
M
Mingyuan Liu, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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