Actively Recruiting

Age: 18Years - 120Years
All Genders
ID05853419

Change History and Adopt a Robotic Solution for Angioplasty Procedure

Led by Robocath · Updated on 2025-08-20

500

Participants Needed

8

Research Sites

4 weeks

Total Duration

On this page

Sponsors

R

Robocath

Lead Sponsor

E

European Cardiovascular Research Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the real-world performance and safety of the R-One System, a robotic device designed to assist in Percutaneous Coronary Intervention (PCI) for patients with coronary artery disease. This single-arm, open-label, multi-center registry aims to confirm the safety, performance, and clinical benefit of the R-One system across up to 15 centers in Europe and South Africa. The study will include 500 adult patients with clinical indications for PCI. Participants will undergo robotic-assisted PCI using the R-One system, which remotely delivers and manipulates coronary guidewires and stent or balloon devices under the operator's control. The system includes the R-One Robotic Platform, a Mobile Radioprotection Screen, and a sterile, single-use consumable kit. Procedures will follow routine hospital practices, current guidelines, and manufacturer instructions. During the study, researchers will assess clinical and technical success of PCI from day 0 to day 3 and during the procedure. They will also monitor radiation exposure to patients and operators, procedure time, contrast volume, fluoroscopy time, and any safety events occurring up to three days post-procedure. Participation involves monitoring during and shortly after PCI to evaluate outcomes and safety.

CONDITIONS

Brief Title

Change History and Adopt a Robotic SolutioN for anGioplasty procedurE

Who Can Participate

Age: 18Years - 120Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of coronary artery disease with clinical indication for PCI
  • Deemed appropriate for robotic-assisted PCI
  • Provided written informed consent after being informed about the study
Not Eligible

You will not qualify if you...

  • Unable or unwilling to provide informed consent, unless waived by ethics committee
  • Investigator determines subject or coronary anatomy unsuitable for robotic-assisted PCI
  • Presence of STEMI
  • Presence of cardiogenic shock
  • Under judicial protection, guardianship, curatorship, or deprived of liberty by judicial or administrative decision

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Day 0

Participants undergo robotic-assisted percutaneous coronary intervention (PCI) performed according to routine hospital practices and current scientific guidelines using the R-One robotic system.

1 procedure visit (in-person)

Surveillance

Duration - Up to 3 days

Participants are observed for safety and clinical outcomes following the robotic-assisted PCI procedure.

Follow-up visits during hospital stay or up to 3 days post-procedure

Trial Site Locations

Total: 8 locations

1

Het Ziekenhuisnetwerk Antwerpen vzw

Antwerp, Belgium, 2000

Actively Recruiting

2

Brest university hospital

Brest, Brittany Region, France, 29609

Actively Recruiting

3

Rouen university hospital

Rouen, France, 76000

Actively Recruiting

4

Centre Cardiologique du Nord

Saint-Denis, Île-de-France Region, France, 93200

Actively Recruiting

5

Rheinland Klinikum Neuss GmbH

Neuss, Lukaskrankenhaus, Germany, 41464

Actively Recruiting

6

San Donato Policlinco Kardia

San Donato Milanese, MI, Italy, 20097

Not Yet Recruiting

7

Polskie Towarzystwo Kardiologiczne

Warsaw, Par Défaut, Poland, 02-507

Not Yet Recruiting

8

Netcare Christiaan Barnard Memorial Hospital

Cape Town, le Cap, South Africa, 8001

Not Yet Recruiting

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Research Team

H

Hamouda Abassi, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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