Actively Recruiting
Change in MAPSE During Treatment of Sepsis
Led by University of Maryland, Baltimore · Updated on 2025-06-19
50
Participants Needed
1
Research Sites
400 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the form of low blood pressure (shock) and heart failure. Ultrasound is frequently used in the emergency department to evaluate why a patient might have low blood pressure. Part of that evaluation may include obtaining ultrasound images and making measurements about how well or poorly the heart is pumping. The investigators will evaluate a certain measurement that relates to cardiac function, determine how it changes in patients before and after they are treated for septic shock. This will involve placing an ultrasound probe on the patient's chest, measuring the upward and downward movement of the mitral valve, the mitral annulus systolic plane excursion (MAPSE), and comparing the measurements before and after treatment is started. The investigators are attempting to determine if this measurement improves before and after treatment.
CONDITIONS
Official Title
Change in MAPSE During Treatment of Sepsis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Sepsis or Septic Shock
You will not qualify if you...
- Age 17 years or younger
- Currently in the emergency department
- Unable to perform point-of-care ultrasound exam due to medical necessity
- Patients without sepsis
- Unable to obtain consent or have a legal representative provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Maryland Medical Center
Baltimore, Maryland, United States, 21201
Actively Recruiting
Research Team
A
Alexis Salerno, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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