Monitoring Eye Pressure Changes in Adults with Open-Angle Glaucoma Using IStent Inject W and a Contact Lens Sensor

What this Trial Is About

Researchers are evaluating fluctuations in eye pressure in glaucoma patients using the Sensimed Triggerfish contact lens sensor CLS. The study compares patients undergoing glaucoma surgery with iStent inject W to those treated only with eye drops and requiring cataract surgery. This prospective controlled study aims to observe changes in intraocular pressure IOP under normal daily conditions before and after surgery. Participants will wear the CLS device for 24 hours during three monitoring visits one month before surgery, and one month and three months after surgery. The device is placed by an ophthalmologist after measuring corneal curvature and records IOP-related fluctuations while participants continue their normal activities and usual eye drop regimen. A control group will undergo similar monitoring before and after cataract surgery without changes to their medical treatment. During the study, participants will attend clinic visits for device placement and removal, eye exams including Goldmann applanation tonometry, and fill out logs recording sleep and medication times. Researchers will analyze fluctuations in IOP over 24 hours, rates of IOP increase and decrease, and sleep-wake slope changes. Follow-up extends to three months post-surgery to assess the durability of surgical effects on IOP variability.

Changes in Eye Pressure in Glaucoma Patients Treated with Istent Inject W, Monitored by a Contact Lens Sensor