Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT06950788

Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant

Led by University of Chicago · Updated on 2026-05-07

60

Participants Needed

1

Research Sites

355 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to establish risk factors for post-transplant in adult individuals with cirrhosis without diabetes undergoing liver transplant evaluation. The question being addressed is: can laboratory work, anthropometric tests, functional tests, imaging, and advanced measurements such as wrist actigraphy, continuous glucose monitoring, or oral glucose tolerance testing predict the development of diabetes after liver transplant? Participants will be asked to periodically participate in wearing a continuous glucose monitor and wrist actigraph and obtain an oral glucose tolerance test both before and after liver transplant.

CONDITIONS

Official Title

Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients presenting to liver transplant clinic with a diagnosis of cirrhosis.
  • Age greater than 18 years.
  • Ability to understand and sign written consent, or have a legally authorized representative to provide consent.
Not Eligible

You will not qualify if you...

  • Patients without consent.
  • Patients with implantable cardioverter defibrillator devices or automated versions excluded from bio-electrical impedance analysis.
  • Patients with unremovable or non-switchable electrical medical devices excluded from bio-electrical impedance analysis.
  • Pregnant patients.
  • Incarcerated patients.
  • Patients diagnosed with type 2 diabetes mellitus more than 5 years ago excluded from oral glucose tolerance testing.

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

University of Chicago Medical Center

Chicago, Illinois, United States, 60637

Actively Recruiting

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Research Team

A

Alan L Hutchison, MD PhD

CONTACT

M

Mary E Rinella, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant | DecenTrialz