Actively Recruiting
Changes in Perioperative Blood Volume and Fluid Distribution in Patients Undergoing Primary Total Hip Replacement.
Led by Copenhagen University Hospital, Hvidovre · Updated on 2025-03-21
25
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Clinical assessment of bleeding and calculation of perioperative blood loss do not provide an accurate estimate of blood volume. This makes rational fluid management difficult, which is of high importance for patient-related outcomes. The availability of carbon monoxide(CO)-rebreathing allows for simple, non-invasive and precise measurement of changes in blood volume. The purpose of the study is to investigate and describe changes in blood volume and fluid distribution perioperative in patients undergoing total hip arthroplasty. Furthermore, to investigate the association between changes in blood volume and incidence of orthostatic insufficiency.
CONDITIONS
Official Title
Changes in Perioperative Blood Volume and Fluid Distribution in Patients Undergoing Primary Total Hip Replacement.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled for an elective total hip arthroplasty (THA) in a standardized fast track setting
- Capable of participating in CO-rebreathing measurement
- Age 65 18 years
- Able to speak and understand Danish
- Has provided written informed consent
You will not qualify if you...
- Intraoperative blood loss exceeding 750 mL
- Perioperative need for a blood transfusion
- Confirmed or suspected coagulopathies
- Factors that make CO-rebreathing measurement impossible
- Known orthostatic intolerance
- American Society of Anesthesiologists physical status (ASA) classification 65 4
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hvidovre University Hospital
Copenhagen, Denmark, 2960
Actively Recruiting
Research Team
P
Puk Kristiansen, MD
CONTACT
A
Ana-Marija Hristovska, Senior registrar, Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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