Deglutitive laryngeal closure in stroke patients.
M L Power, S Hamdy, S Singh...
https://pubmed.ncbi.nlm.nih.gov/17012336/Actively Recruiting
Led by University of Giessen · Updated on 2023-12-01
200
Participants Needed
1
Research Sites
95 weeks
Total Duration
Researchers are investigating changes in swallowing, taste, and smell in patients who have had a stroke. This study focuses on how stroke affects swallowing by measuring sensitivity in swallowing-related areas and assessing neuropsychological issues like swallowing apraxia. The research also compares results with younger and older healthy volunteers to better understand these changes after stroke. The study involves diagnostic tests including flexible endoscopic evaluation of swallowing FEES for stroke patients, measuring sensitivity thresholds with a pudendal electrode, taste and smell tests, and neuropsychological assessments for cognitive issues related to swallowing. Control groups consist of younger and older volunteers who can consent to participate. Participants will undergo assessments within 96 hours after their initial stroke symptoms, including swallowing function, neuropsychological deficits, lesion site imaging, sensitivity, and tastesmell testing. Healthy volunteers provide baseline comparison data. The study is observational and aims to better understand swallowing difficulties and sensory changes in stroke patients. Participation includes diagnostic tests and cognitive assessments conducted shortly after stroke onset.
CONDITIONS
Changes in Sensitivity, Taste and Smell in Stroke Patients
T
Tobias Braun, M.D.
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University of Giessen
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - Up to 72 hours from stroke onset for stroke patients
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility confirmation and consent
Duration - Within 96 hours after initial symptoms
Participants undergo tests to assess swallowing sensitivity, taste, smell, and neuropsychological function.
1 to 2 visits depending on participant group and assessments
Duration - Up to 96 hours after initial symptoms
Participants are observed for changes in dysphagia and neuropsychological deficits after initial assessments.
Follow-up visits as scheduled within 4 days
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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https://pubmed.ncbi.nlm.nih.gov/8108539/University of Giessen
Lead Sponsor