Actively Recruiting
Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients
Led by University Hospital Ostrava · Updated on 2025-05-04
80
Participants Needed
4
Research Sites
139 weeks
Total Duration
On this page
Sponsors
U
University Hospital Ostrava
Lead Sponsor
U
University Hospital Bulovka
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a non-interventional study that will not pose any burden for the participants. The study subjects will be examined and treated in a standard manner according to current clinical recommendations for the treatment of overactive bladder (OAB). A portion of urine samples, which are routinely collected for biochemical and culture examinations as part of the diagnostic process, will be sent for examination of the characteristics of the urinary microbiome and metabolome (UMM) before and after treatment.
CONDITIONS
Official Title
Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult women over 18 years of age
- Written consent to participate in the study
- Willingness to undergo OAB evaluation and treatment according to the protocol
- OAB symptoms lasting longer than 3 months
- At least 3 episodes of severe urgency with or without urge incontinence within 3 days documented by voiding diary
- OAB symptom score V8 questionnaire 2;8
You will not qualify if you...
- Known congenital developmental defects of the urinary tract such as congenital hydronephrosis, vesicoureteral reflux, renal agenesis, hypoplasia, multicystic or polycystic kidneys
- Any previous treatment for OAB
- Recurrent urinary tract infections with more than 3 episodes in the last 12 months
- Presence of a foreign body in the urinary tract including urolithiasis, urinary catheter, or ureteral stent
- Acute or chronic diseases that may affect lower urinary tract function
- Rheumatoid arthritis
- Diabetes mellitus
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
University Hospital Ostrava
Ostrava, Moravian-Silesian Region, Czechia, 70852
Actively Recruiting
2
Thomayer University Hospital
Prague, Czechia, 14059
Actively Recruiting
3
Institute of Microbiology of the Czech Academy of Sciences
Prague, Czechia, 14200
Actively Recruiting
4
University Hospital Bulovka
Prague, Czechia, 18081
Actively Recruiting
Research Team
J
Jiří Hynčica
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here