Actively Recruiting
Characterising the Neuromuscular Function of Stroke Patients During Recovery
Led by University of Nottingham · Updated on 2025-06-10
16
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Strokes are a leading cause of death and disability worldwide, especially impacting developed countries with significant social and economic effects. This research aims to better understand the neuromuscular deficits caused by stroke to improve future rehabilitation methods. The study focuses on patients who have experienced a stroke within the last five years and continue to have difficulties with one side of their body. Participants will undergo assessments of their neuromuscular function, including tests of muscle strength and activation using specialized electromyography techniques. The study involves a single testing session where motor control, balance, and muscle function of both upper and lower limbs will be evaluated. These assessments aim to provide detailed information about muscle activation patterns and physical abilities post-stroke. During their participation, individuals will complete various motor control tasks, balance tests, and dexterity assessments such as the Grooved Pegboard Test and Trail Making Test. Researchers will measure muscle strength and coordination using isometric dynamometry and electromyography. The data collected will help inform the development of tailored rehabilitation interventions to support stroke recovery. Participation involves one baseline testing session, and safety and functional outcomes will be closely monitored.
CONDITIONS
Brief Title
Characterising the Neuromuscular Function of Post Stroke Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 40 and 85 years
- Willing and able to give informed consent for participation
- Had a confirmed stroke within the last 5 years
- Self-reports persistent loss of unilateral limb function after stroke
You will not qualify if you...
- Diagnosis of cognitive impairment or dementia
- Current or recent (less than 2 years) malignancy
- Severe respiratory disease such as uncontrolled asthma, COPD, or pulmonary hypertension
- Active cardiovascular disease including uncontrolled hypertension, recent cardiac events, heart failure class III/IV, significant arrhythmia, or unstable angina
- Untreated metabolic diseases such as hyper/hypoparathyroidism or Cushing's disease
- Significant musculoskeletal disorders
- Dialysis patients
- Recent steroid treatment within 6 months or hormone replacement therapy
- Wheelchair dependent for mobility
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants complete a single testing session involving assessments of neuromuscular function, including electromyography, motor control, balance, and dexterity tests.
1 visit (in-person)
Duration - Up to 5 years post-stroke
Participants are observed over time to characterize neuromuscular function during stroke recovery without active intervention.
visit schedule not specified
Trial Site Locations
Total: 1 location
1
Royal Derby Hospital branch, School of Medicine, University of Nottingham
Derby, Derbyshire, United Kingdom, DE22 3DT
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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