Actively Recruiting

Age: 40Years - 85Years
All Genders
NCT07013188

Characterising the Neuromuscular Function of Post Stroke Patients

Led by University of Nottingham · Updated on 2025-06-10

16

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Strokes are a leading cause of death and disability in developed countries, with significant economic and social impacts. Defined by the WHO, strokes cause rapid and lasting disturbances in cerebral function. In the UK, strokes occur every five minutes, affecting 100,000 people annually and resulting in substantial physical impairments and financial costs. Although stroke-related deaths have decreased due to improved treatments and awareness, strokes remain a major cause of death and disability worldwide, especially in lower-income countries. Strokes typically cause unilateral deficits, leading to significant daily challenges and necessitating tailored rehabilitation strategies such as CIMT, FES, and VR Rehab. As the population ages, innovative neurorehabilitation approaches are essential to enhance functional recovery post-stroke. This pilot study aims to better understand the neuromuscular deficits caused by stroke to inform and improve future rehabilitation interventions, including the potential use of force accuracy training (FAT)

CONDITIONS

Official Title

Characterising the Neuromuscular Function of Post Stroke Patients

Who Can Participate

Age: 40Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 40-85 years
  • Willing and able to give informed consent for participation in the study
  • Had a confirmed stroke within the last 5 years
  • Self-reports persisting post-stroke loss of unilateral limb function
Not Eligible

You will not qualify if you...

  • Diagnosis of cognitive impairment or dementia
  • Current or recent (less than 2 years) malignancy
  • Severe respiratory disease such as uncontrolled asthma, COPD, or pulmonary hypertension
  • Active cardiovascular disease including uncontrolled hypertension (BP >160/100 mmHg), recent cardiac event (within 12 months), heart failure (Class III/IV), significant arrhythmia, or unstable angina
  • Metabolic diseases like untreated hyper/hypoparathyroidism or Cushing's disease
  • Significant musculoskeletal disorders based on clinical opinion
  • Dialysis patients
  • Recent steroid treatment within 6 months or hormone replacement therapy
  • Wheelchair dependency for mobility

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Royal Derby Hospital branch, School of Medicine, University of Nottingham

Derby, Derbyshire, United Kingdom, DE22 3DT

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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