Actively Recruiting
The Characteristics of Gut Microbiota in Patients With Sarcopenia and the Development of Probiotics
Led by Seoul National University Bundang Hospital · Updated on 2026-01-12
150
Participants Needed
1
Research Sites
28 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary aim of this study is to identify the composition and characteristics of the gut microbiota in patients with sarcopenia in older adults, and compare these with the gut microbiota characteristics of older adults and young control groups to determine differences. Secondary purpose of this study is to provide data on the characteristics of gut microbiota for the development of probiotics effective in treating sarcopenia in older adults.
CONDITIONS
Official Title
The Characteristics of Gut Microbiota in Patients With Sarcopenia and the Development of Probiotics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals aged 65 to 90 years with sarcopenia diagnosed by 2019 AWGS guidelines including low muscle mass, low strength, or low physical performance
- Individuals aged 65 to 90 years as older adult controls
- Individuals aged 20 to 50 years as young adult controls
- All participants must voluntarily agree and sign informed consent
You will not qualify if you...
- Currently receiving treatment for severe diseases of cardiovascular, immune, respiratory, gastrointestinal/hepatic and biliary, renal/urinary, neurological, psychiatric systems, infectious diseases, or malignant tumors (except non-melanoma skin tumors); cancer survivors only if less than 5 years remission
- Difficulty with independent daily activities due to musculoskeletal or neurological diseases or cognitive impairment
- Regularly consuming alcohol above WHO daily limits (≥40 g/day men, ≥20 g/day women)
- Heavy smokers (≥20 cigarettes/day)
- Elevated liver enzymes (AST or ALT ≥ 3 times upper normal limit)
- Uncontrolled hypertension (systolic ≥ 140 mmHg or diastolic ≥ 90 mmHg after rest)
- Uncontrolled diabetes mellitus (HbA1c > 7.0%)
- Abnormal thyroid stimulating hormone levels (TSH ≤ 0.1 or ≥ 10 µIU/mL)
- Deemed unsuitable by investigator for other reasons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea, 13620
Actively Recruiting
Research Team
J
Jae-Young Lim
CONTACT
B
Bo-Ram Kim
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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