Actively Recruiting
Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study
Led by Rigshospitalet, Denmark · Updated on 2026-04-01
100
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
Sponsors
R
Rigshospitalet, Denmark
Lead Sponsor
B
Bispebjerg Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Despite high success rates of hip and knee arthroplasty, up to 20% of patients report moderate-to-severe pain (NRS \> 3) persisting beyond the expected healing period. This investigator-initiated, descriptive cohort study will re-invite approximately 100 consenting patients with persistent postoperative pain-identified from a pool of \~7 000 respondents-to complete standardized assessments of neuropathic (DN4), nociplastic (IASP criteria + Fibromyalgia Survey Questionnaire) and nociceptive (KOOS/HOOS pain domains) pain. Primary outcomes are the prevalence of potential nociplastic pain and the proportion experiencing significant pain in two or more mechanistic categories. Secondary analyses will compare baseline vs. re-evaluated DN4 scores, FSQ and KOOS/HOOS distributions, and examine differences between patients with and without possible neuropathic pain. Findings will inform targeted pre- and postoperative pain management strategies.
CONDITIONS
Official Title
Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Persistent moderate to severe pain (NRS > 3) after total hip arthroplasty (THA), total knee arthroplasty (TKA), or unicompartmental knee arthroplasty (UKA)
- Willingness to be contacted for study participation
You will not qualify if you...
- History of re-operation after the arthroplasty
- Prosthetic dislocation (luxation)
- Unwillingness to be contacted for the study
- Postoperative complications such as prosthesis infection, thromboembolism, or fracture of the prosthesis
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Rigshospitalet
Østerbro, København Ø, Denmark, 2100
Actively Recruiting
Research Team
M
Milan Mohammad, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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