Study of Persistent Moderate to Severe Pain After Total Hip or Knee Replacement Surgery Assessing Different Types of Pain in Patients Experiencing Ongoing Pain After Arthroplasty

What this Trial Is About

Researchers are investigating the types of persistent pain experienced by patients after total hip or knee arthroplasty, including total knee arthroplasty TKA, total hip arthroplasty THA, and unicompartmental knee arthroplasty UKA. Despite high success rates of these surgeries, up to 20% of patients report moderate to severe pain that continues beyond normal healing. The study aims to identify the prevalence of different types of pain, such as neuropathic, nociplastic, and nociceptive pain, to better understand and improve pain management before and after surgery. This observational study will re-invite about 100 patients with persistent postoperative pain from an initial group of approximately 7,000 respondents who consented to further contact. Participants will complete standardized questionnaires assessing neuropathic pain DN4, nociplastic pain IASP criteria and Fibromyalgia Survey Questionnaire, and nociceptive pain KOOSHOOS pain domains. The study will compare current pain assessments with previous baseline results and explore differences between patients with and without neuropathic pain. Participants will provide detailed responses through questionnaires regarding their pain experience, satisfaction with surgery outcomes, and considerations for potential re-operation. Researchers will analyze the prevalence of nociplastic pain and the proportion of patients experiencing significant pain in multiple categories. Follow-up assessments will occur one year after surgery to evaluate changes in pain scores using validated tools. The findings aim to guide targeted pain management strategies for patients undergoing hip or knee arthroplasty.

Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study