Actively Recruiting

Age: 19Years - 100Years
All Genders
NCT07053254

The Characteristics and Treatment Mechanism of Vascular Grafts in Elderly Patients With CAOD Through Single-cell Transcriptome Analysis

Led by Yonsei University · Updated on 2025-07-08

100

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to establish a cardiovascular biobank using vascular grafts obtained from participants with coronary artery occlusive disease (CAOD). Through genomic and transcriptomic analyses, the study seeks to characterize the biological features of the vascular grafts and identify potential therapeutic targets and mechanisms related to vascular remodeling and stiffness.

CONDITIONS

Official Title

The Characteristics and Treatment Mechanism of Vascular Grafts in Elderly Patients With CAOD Through Single-cell Transcriptome Analysis

Who Can Participate

Age: 19Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 19 years or older
  • Scheduled to undergo coronary artery bypass grafting (CABG)
  • Provide voluntary written informed consent for study participation
  • Able and willing to comply with study procedures during the study period
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Require concomitant surgical correction for valvular heart disease
  • Undergoing reoperative (redo) cardiac surgery
  • Decline to provide informed consent prior to surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Division of Cardiovascular Surgery, Severance Cardiovascular Hospital , Yonsei University College of Medicine

Seoul, South Korea, 120-752

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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The Characteristics and Treatment Mechanism of Vascular Grafts in Elderly Patients With CAOD Through Single-cell Transcriptome Analysis | DecenTrialz