Actively Recruiting
Characterization of Acute Pain
Led by Children's National Research Institute · Updated on 2026-01-14
100
Participants Needed
1
Research Sites
130 weeks
Total Duration
On this page
Sponsors
C
Children's National Research Institute
Lead Sponsor
V
VentureWell
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to better understand how acute pain and responses to pain treatment can be measured in children and adolescents using a non-invasive device. Pain is usually assessed using self-reported or observational scales, which can be difficult to interpret, especially in pediatric patients. This study will evaluate whether a novel device, the AlgometRx Nociometer, can provide an objective measure of nociceptive pain. Participants ages 6 to 21 years who are undergoing elective surgery or bone marrow transplantation will be enrolled at Children's National Hospital. The device measures changes in pupil size in response to gentle electrical stimulation, which reflects activity in pain-related nerve pathways. Measurements will be taken before and after procedures and during routine hospital care, alongside standard pain assessments. This is an observational study. Participation will not change or guide any medical treatment, and all pain management will follow standard clinical care. The information collected may help improve future pain assessment and treatment for pediatric patients.
CONDITIONS
Official Title
Characterization of Acute Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children and adolescents ages 6 to 21 years
- Undergoing elective surgical procedures without a history of chronic pain, OR undergoing or planning to undergo bone marrow transplantation (BMT)
- Able to provide written informed assent and parental permission/consent, as applicable
You will not qualify if you...
- Documented history of eye disease that precludes pupillometry
- Unwilling or unable to participate
AI-Screening
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Trial Site Locations
Total: 1 location
1
Children's National Hospital
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
Research Team
J
Julia Finkel, M.D
CONTACT
S
Shaghayegh Rezalou
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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