Study of Vocal Cord Lesions Causing Voice Problems in Adults with Systemic Autoimmune Diseases

What this Trial Is About

Researchers are conducting a multicenter retrospective observational study to identify and describe vocal cord lesions that cause dysphonia in patients with systemic autoimmune diseases. The study focuses on understanding the types of lesions, such as bamboo nodes and other specific or non-specific lesions, their diagnosis timing, and treatment approaches in conditions like rheumatoid arthritis, systemic lupus erythematosus, and other connective tissue diseases. The study involves reviewing medical records from January 2014 to December 2024 to characterize vocal cord lesions responsible for dysphonia. The research examines patient histories for lesions like fibrosis, immune complex deposits, rheumatoid nodules, granulomas, and other mucosal abnormalities. Treatment methods like vocal therapy, oral steroids, surgery, and avoiding irritants are noted, though management varies due to the rarity of these conditions. Participants records will be reviewed for lesion type as diagnosed by specialists such as otorhinolaryngologists or rheumatologists. The study assesses diagnosis delays, lesion management, and associated risk factors. Participants will not undergo new treatments but will have their medical histories analyzed to better understand dysphonia causes in autoimmune disease contexts.

Characterization of "Bamboo" and Other Vocal Cord Lesions Responsible for Dysphonia in Patients With Systemic Autoimmune Diseases (BAMBOO)