Actively Recruiting
Characterization of "Bamboo" and Other Vocal Cord Lesions Responsible for Dysphonia in Patients With Systemic Autoimmune Diseases
Led by University Hospital, Brest · Updated on 2025-01-17
150
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting a multicenter retrospective observational study to identify and describe vocal cord lesions that cause dysphonia in patients with systemic autoimmune diseases. The study focuses on understanding the types of lesions, such as "bamboo nodes" and other specific or non-specific lesions, their diagnosis timing, and treatment approaches in conditions like rheumatoid arthritis, systemic lupus erythematosus, and other connective tissue diseases. The study involves reviewing medical records from January 2014 to December 2024 to characterize vocal cord lesions responsible for dysphonia. The research examines patient histories for lesions like fibrosis, immune complex deposits, rheumatoid nodules, granulomas, and other mucosal abnormalities. Treatment methods like vocal therapy, oral steroids, surgery, and avoiding irritants are noted, though management varies due to the rarity of these conditions. Participants' records will be reviewed for lesion type as diagnosed by specialists such as otorhinolaryngologists or rheumatologists. The study assesses diagnosis delays, lesion management, and associated risk factors. Participants will not undergo new treatments but will have their medical histories analyzed to better understand dysphonia causes in autoimmune disease contexts.
CONDITIONS
Brief Title
Characterization of "Bamboo" and Other Vocal Cord Lesions Responsible for Dysphonia in Patients With Systemic Autoimmune Diseases (BAMBOO)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years or older
- Diagnosed with a systemic autoimmune disease such as rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, primary Sjogren disease, sarcoidosis, vasculitis, myositis, Still disease, or Sharp syndrome
- Experiencing dysphonia (voice difficulties)
- Having a vocal cord or laryngeal lesion identified
You will not qualify if you...
- Patients under 18 years of age
- Dysphonia caused by vocal cord palsy related to neurological conditions or cancer
- History of neck radiation therapy
- History of oro-tracheal intubation
- Diagnosis of laryngeal cancer
- Refusal to participate
- Unable to give consent
- Under legal protection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Retrospective data collection covering patients from January 2014 to December 2024
Participants undergo evaluation to identify the nature of vocal cord lesions responsible for their dysphonia.
1 visit (in-person) for assessment
Duration - Up to 11 years retrospective observation
Participants' medical records are reviewed to assess diagnosis delays, management, and outcomes of vocal cord lesions.
No additional visits required; data collected from medical records
Trial Site Locations
Total: 1 location
1
Chu Brest
Brest, France, 29609
Actively Recruiting
Research Team
A
Alice TISON
C
Clément SARRAUSTE
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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