Actively Recruiting
Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
Led by Mayo Clinic · Updated on 2026-02-17
300
Participants Needed
1
Research Sites
721 weeks
Total Duration
On this page
Sponsors
M
Mayo Clinic
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research is to create a collection of bile, bile duct brushings and medical information from people with Primary Sclerosing Cholangitis (PSC) and controls to learn more about changes that occur in the liver.
CONDITIONS
Official Title
Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with Primary Sclerosing Cholangitis (PSC) between 18 and 85 years old
- Diagnosis based on clinical and biochemical evidence of chronic cholestasis lasting at least six months, positive cholangiographic findings, and compatible liver biopsies if available
- Women with PSC who are pregnant or of childbearing potential may enroll
- Patients with PSC and Cholangiocarcinoma are eligible
- Control participants without history of PSC or other chronic liver diseases, aged 18 to 85, of any gender
You will not qualify if you...
- Unable to provide informed consent
- Prisoners or institutionalized individuals
- Patients with PSC who have had an orthotopic liver transplant
- History of Roux En Y surgical procedure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
E
Erik Schlicht, CCRP
CONTACT
J
Jackie Bianchi
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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