Actively Recruiting
Characterization of Hepatopathy in Turner Syndrome: Analysis of Determinants in an Observational Study
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-27
120
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to investigate the prevalence of liver changes in adult patients with Turner Syndrome (TS) and explore the possible causes behind these changes. The study seeks to understand how biochemical and structural liver abnormalities are related and to provide important insights into the development of liver disease in TS patients. The study is observational and retrospective, involving patients with TS who are monitored over time at a specialized endocrinology center. These patients were diagnosed by karyotype analysis and have undergone clinical evaluations including measurements of body parameters and medical history reviews focusing on metabolic and autoimmune conditions. Information about menstrual cycles and hormone replacement therapies will also be collected, along with laboratory tests. Participants will have their medical history and liver health data reviewed, including comparisons of liver function and structure using imaging techniques like fibroscan. Researchers will assess factors related to liver disease presence and progression. The study involves no experimental treatments, focusing on observation and data collection, with participant involvement primarily through clinical record review and laboratory assessments.
CONDITIONS
Brief Title
Characterization of Hepatopathy in Turner Syndrome: Analysis of Determinants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Turner syndrome made by karyotype analysis on peripheral blood.
- Age 18 years or older
- Written informed consent obtained
You will not qualify if you...
- TS patients on therapy with drugs responsible for significant liver enzyme alterations (liver function alteration, LFA).
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Ongoing throughout the study period
Participants with Turner Syndrome who undergo routine clinical evaluations and laboratory investigations as part of their standard care are observed over time.
Periodic visits according to routine clinical practice
Trial Site Locations
Total: 1 location
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy, 40138
Actively Recruiting
Research Team
A
Alessandra Gambineri, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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