Study of Liver Disease in Adult Women with Turner Syndrome Observational Analysis of Liver Function and Related Factors

What this Trial Is About

This research aims to investigate the prevalence of liver changes in adult patients with Turner Syndrome TS and explore the possible causes behind these changes. The study seeks to understand how biochemical and structural liver abnormalities are related and to provide important insights into the development of liver disease in TS patients. The study is observational and retrospective, involving patients with TS who are monitored over time at a specialized endocrinology center. These patients were diagnosed by karyotype analysis and have undergone clinical evaluations including measurements of body parameters and medical history reviews focusing on metabolic and autoimmune conditions. Information about menstrual cycles and hormone replacement therapies will also be collected, along with laboratory tests. Participants will have their medical history and liver health data reviewed, including comparisons of liver function and structure using imaging techniques like fibroscan. Researchers will assess factors related to liver disease presence and progression. The study involves no experimental treatments, focusing on observation and data collection, with participant involvement primarily through clinical record review and laboratory assessments.

Characterization of Hepatopathy in Turner Syndrome: Analysis of Determinants