Study of Metabolic and Hormonal Features in Women Aged 18 to 45 with Polycystic Ovary Syndrome

What this Trial Is About

Polycystic ovary syndrome PCOS is a common hormonal disorder affecting women before menopause, often marked by high testosterone levels, excess hair growth, body fat, irregular periods, and difficulties with fertility. PCOS is linked to diabetes and heart disease, and women with PCOS may experience higher stress hormone levels, which can impact their quality of life. This study aims to measure stress hormone levels in urine and assess quality of life through questionnaires, while also examining body composition and bone structure using specialized scans. Participants who meet at least two of the three Rotterdam criteria for PCOSirregular menstrual cycles, signs of high androgen levels, or polycystic ovarieswill be included. The study collects fasting blood samples for a biobank, and uses DXA and ExtremeCT scans to evaluate bone density and architecture. This observational study focuses on characterizing women with PCOS without administering any treatments. During the study, participants will complete questionnaires about their quality of life and provide urine and blood samples for hormone analysis. They will undergo body scans to assess bone density and structure at the start of the study. Researchers will monitor bone mass density as the primary outcome and stress hormone levels as a secondary outcome. The study follows participants over time to better understand PCOS and its impact on health and well-being.

Characterization of a Prospective Cohort of Women With PCOS