Actively Recruiting
Characterizing the Microvascular Environment of Bladder Cancer With Super-Resolution Ultrasound Localization Microscopy
Led by Duke University · Updated on 2026-05-04
30
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The project will include 30 patients with bladder cancer who are candidates for bladder removal. After signing the consent form, the study team will collect some clinical data, such as age, past medical history, past surgical history, and information about your current disease. At the day of surgery, after putting participants into sleep and before surgery begins, the study team will do a novel ultrasound called "Super-Resolution Ultrasound Localization Microscopy" to check if there is still disease in the bladder. The team will then compare the results of this investigational ultrasound with the final pathology and other imaging studies.
CONDITIONS
Official Title
Characterizing the Microvascular Environment of Bladder Cancer With Super-Resolution Ultrasound Localization Microscopy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years or older
- Histological evidence of urothelial cancer of the bladder
- Recommended for radical cystectomy by the treating physician (including muscle-invasive bladder cancer or high-risk non-muscle-invasive bladder cancer such as high-grade T1 BCG refractory and worrisome histological variants)
You will not qualify if you...
- Known or suspected allergy to sulfur hexafluoride lipid microsphere or its components like polyethylene glycol (PEG)
- Pregnancy or breastfeeding
- Decline to participate in the study
- History of serious allergic reactions to COVID-19 vaccination
- Unstable medical conditions such as current hospitalization, ICU stay, or high-risk cardiac disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Duke University
Durham, North Carolina, United States, 27710
Actively Recruiting
Research Team
M
Michael Abern, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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