Actively Recruiting
CHART Study of Coronary CT Angiography in Coronary Artery Disease
Led by Shanghai Zhongshan Hospital · Updated on 2022-05-25
5000
Participants Needed
1
Research Sites
834 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In a cohort of patients referred to coronary computed tomography angiography (CCTA), the investigators aim: 1. To describe the natural history of the coronary atherosclerotic plaque development and progression or regression, as well as the plaque characterization and phenotypes over time by CCTA among deferred coronary lesions 2. To explore the precursors of plaques leading to acute coronary syndrome (ACS) or chronic coronary syndrome (CCS) in deferred coronary lesions 3. To investigate prognostic implication of qualitative and quantitative plaque analysis of stenosis and plaque features, disease patterns, hemodynamic parameters, and fat metrics on CCTA along with physiologic assessment 4. To investigate the effects of different treatment strategies according to stenosis and plaque features, fat metrics on CCTA along with physiologic assessments.
CONDITIONS
Official Title
CHART Study of Coronary CT Angiography in Coronary Artery Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with an indication for coronary CT angiography (CCTA)
- Patients who have signed a written informed consent form
You will not qualify if you...
- Left ventricular ejection fraction less than 35%
- Acute ST-elevation myocardial infarction within 72 hours or previous coronary artery bypass graft surgery
- Abnormal epicardial coronary flow (TIMI flow less than 3)
- Planned coronary artery bypass graft surgery after diagnostic angiography
- Poor quality of CCTA or other reasons making analysis unsuitable by core lab
- Patients with a stent in the target vessel
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Shanghai Zhongshan Hospital
Shanghai, China
Actively Recruiting
Research Team
N
Neng Dai, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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