Actively Recruiting

Early Phase 1
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT07337434

To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital

Led by Syeda Sana Zaman · Updated on 2026-01-13

106

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to compare efficacy of methotrexate vs apremilast in the management of chronic plaque psoriasis.Given the high prevalence of psoriasis in Pakistan and the significant psychological impact on patients, particularly in Peshawer,this study will provide valuable insights into optimal treatment strategies.

CONDITIONS

Official Title

To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 60 years
  • Either gender
  • Diagnosed with moderate to severe plaque psoriasis with PASI score of 10 or higher
  • No systemic therapy for psoriasis in the past 3 months
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • History of liver or kidney dysfunction
  • Known allergy to methotrexate or apremilast

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

MTI-HMC Peshawar

Peshawar, Khyber Pukhtunkhwa, Pakistan, 25000

Actively Recruiting

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Research Team

F

Filza Ajmal, FCPS part 2

CONTACT

G

Ghafoor Ullah

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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