Actively Recruiting
Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer
Led by The First Affiliated Hospital of Henan University of Science and Technology · Updated on 2025-02-10
196
Participants Needed
2
Research Sites
578 weeks
Total Duration
On this page
Sponsors
T
The First Affiliated Hospital of Henan University of Science and Technology
Lead Sponsor
J
Jiangsu HengRui Medicine Co., Ltd.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this study is to compare outcomes in Chinese patients with locally advanced resectable esophageal squamous cell cancer who have received either surgery or definitive chemoradiation (CRT) by the randomized, open-label, multicenter trial.
CONDITIONS
Official Title
Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chinese ethnicity
- Diagnosed with esophageal squamous cell cancer
- Cancer located in the mid or lower esophagus
- Tumor is considered resectable
- Clinical stage cT1bN+M0 or cT2-4aN0-2M0
You will not qualify if you...
- Presence of distant metastasis to solid visceral organs
- Local invasion into trachea, descending aorta, or recurrent laryngeal nerve
- Serious pre-existing conditions or poor physical status that prevent thoracotomy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Anyang Tumor Hospital
Anyang, Henan, China
Actively Recruiting
2
The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology
Luoyang, Henan, China, 471003
Actively Recruiting
Research Team
S
Shegan Gao, MD, PhD
CONTACT
R
Ruinuo Jia, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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