Actively Recruiting
Chemosensitivity During Phases of the Menstrual Cycle in Breast Cancer Patients
Led by The Netherlands Cancer Institute · Updated on 2025-11-26
100
Participants Needed
1
Research Sites
561 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a prospective, multicenter study in which a serum sample will be collected at the day of starting neo adjuvant treatment in breast cancer patients
CONDITIONS
Official Title
Chemosensitivity During Phases of the Menstrual Cycle in Breast Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women with a new diagnosis of triple negative breast cancer who have not yet started systemic treatment
- Patients with stage I-III disease or locoregional recurrence who have not been treated with chemotherapy before
- Aged under 60 years
- Women having a regular physiological menstrual cycle
- Patients assigned to receive neoadjuvant chemotherapy with or without immunotherapy, targeted therapy, and endocrine therapy
- Patients must be systemic treatment naïve for current malignancy (no chemotherapy, hormonal therapy, or targeted therapy)
- Signed written informed consent
You will not qualify if you...
- Current use of hormonal contraception or use within six weeks prior to starting neoadjuvant systemic treatment, including oral contraception, hormonal intra-uterine device, nuva-ring, Implanon, prikpil, or other forms
- No ovarian function suppression to preserve fertility
- Currently pregnant and/or breastfeeding
- If hormonal contraception or breastfeeding in the last year, patients must have had at least two menstrual cycles since stopping hormonal contraception
- Active other malignancy
- IVF trajectory for egg cell preservation prior to starting neoadjuvant systemic treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Antoni van Leeuwenhoek
Amsterdam, North Holland, Netherlands, 1066CX
Actively Recruiting
Research Team
S
Sabine Linn, MD
CONTACT
I
Ingrid Mandjes
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here