Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06280508

Chemotherapy Combined With Adebrelimab and Apatinib as the Perioperative Treatment in Patients With Biliary Tract Cancer

Led by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Updated on 2024-04-23

40

Participants Needed

1

Research Sites

213 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, single-arm exploratory study to evaluate the efficacy and safety of chemotherapy combined with Adebrelimab and Apatinib as the perioperative treatment in Patients With Biliary Tract Cancer.

CONDITIONS

Official Title

Chemotherapy Combined With Adebrelimab and Apatinib as the Perioperative Treatment in Patients With Biliary Tract Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed intrahepatic cholangiocarcinoma
  • Tumor lesion that can be surgically removed
  • No contraindications to surgery
  • High risk of tumor recurrence
  • No prior systemic therapy for intrahepatic cholangiocarcinoma
  • ECOG Performance Status of 0 or 1
  • Child-Pugh Class Grade A
Not Eligible

You will not qualify if you...

  • History of gastrointestinal hemorrhage within 6 months prior to study treatment or a clear tendency for gastrointestinal hemorrhage
  • Abdominal fistula, gastrointestinal perforation, or intraperitoneal abscess within 6 months prior to study treatment
  • Known genetic or acquired bleeding or clotting disorders
  • Thrombosis or thromboembolic events within 6 months prior to study treatment
  • Uncontrolled cardiac symptoms or disease
  • Hypertension not well controlled by medication

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Guangzhou, China/Guangdong, China

Actively Recruiting

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Research Team

Y

Yajin Chen

CONTACT

C

Changzhen shang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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