Actively Recruiting
CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma
Led by Washington University School of Medicine · Updated on 2026-01-16
2000
Participants Needed
7
Research Sites
149 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Purpose: This study aims to improve asthma care by helping clinicians at community health centers prescribe a guideline-recommended treatment called SMART (Single Maintenance and Reliever Therapy). The investigators will provide training and resources to clinicians, give feedback on prescribing patterns, and offer educational tools for patients and providers. The investigators will roll out these resources in stages across clinics. The study will measure how well the program helps clinicians prescribe SMART therapy and whether it reduces asthma exacerbations in patients.
CONDITIONS
Official Title
CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinics actively participate in the St. Louis Integrated Health Center Network for Community Academic Partnerships
- Clinics employ at least 3 clinicians who regularly manage adult asthma patients weekly
- Clinics provide data to Azara for data queries
- Clinics can receive all parts of the SMART implementation bundle including education, practice support, audit and feedback, patient education aides, and participate in monthly committee meetings
- Clinicians or clinical staff provide signed informed consent
- Clinicians have current state licenses as physician, assistant physician, nurse practitioner, or physician assistant
- Clinicians regularly care for adults with asthma
- Clinicians are willing and able to integrate the SMART bundle into their practice
- Clinicians can participate through all study phases and share prescribing and asthma outcome data
- Patients are 12 years old or older
- Patients have a coded diagnosis of asthma
- Patients had two or more asthma exacerbations in the past year requiring systemic corticosteroids or have an active prescription for medium or higher dose maintenance inhaled corticosteroids or low dose or higher ICS-LABA inhalers with reliever inhalers
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 7 locations
1
Affinia healthcare, 2220 Lemp Ave
St Louis, Missouri, United States, 63104
Not Yet Recruiting
2
Affinia healthcare, 1717 Biddle Street
St Louis, Missouri, United States, 63106
Not Yet Recruiting
3
Affinia healthcare, 4414 North Florissant Avenue
St Louis, Missouri, United States, 63107
Actively Recruiting
4
Family Care Heath Center, 4352 Manchester Ave
St Louis, Missouri, United States, 63110
Not Yet Recruiting
5
Washington University in St. Louis School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
6
Family Care Heath Center, 401 Holly Hills Ave
St Louis, Missouri, United States, 63111
Not Yet Recruiting
7
Affinia healthcare, 3396 Pershall Road,
St Louis, Missouri, United States, 63135
Not Yet Recruiting
Research Team
J
James Krings, MD MSCI
CONTACT
K
Krutika Chauhan, MBBS MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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