Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05089162

CHF-COV Reduced (Chronic Heart Failure With Reduced Ejection Fraction - COngestion eValuation)

Led by Pr. Nicolas GIRERD · Updated on 2023-06-05

200

Participants Needed

1

Research Sites

391 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Heart failure (HF) is a significant cause of death and the leading cause of hospitalization in patients over 65 years of age. Congestion is the main source of symptoms and the leading cause of hospitalization for HF. Furthermore, congestive signs identified in asymptomatic patients are associated with the risk of developing symptomatic HF. The literature supports a multi-modality / integrative evaluation of congestion, combining clinical examination, laboratory results and ultrasound evaluation. The main objective of the CHF-COVReduced study is to identify congestion markers (clinical, biological and ultrasound) quantified during a consultation or day hospitalization for the monitoring of chronic HF with reduced left ventricular ejection fraction that are associated with the risk of all-cause death, hospitalization for acute HF or IV diuretics injection in a day hospital.

CONDITIONS

Official Title

CHF-COV Reduced (Chronic Heart Failure With Reduced Ejection Fraction - COngestion eValuation)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with chronic heart failure and reduced or moderately reduced left ventricular ejection fraction admitted for scheduled day hospitalization or consultation
  • Left ventricular ejection fraction less than 40% or between 40 and 50%
  • Age 18 years or older
  • Patients who have received complete information about the study and signed informed consent
  • Patients affiliated with or beneficiaries of a social security scheme
Not Eligible

You will not qualify if you...

  • Life expectancy of 3 months or less due to other illnesses
  • Dialysis patients (peritoneal or hemodialysis) or those with glomerular filtration rate below 15 ml/min/m2
  • History of lung surgery such as lobectomy or pneumonectomy
  • Severe lung or pleural diseases preventing reliable lung ultrasound (e.g., severe emphysema, chronic pleurisy, pulmonary fibrosis)
  • Pregnant women, parturient, or nursing mothers
  • Adults under legal protection measures (guardianship, curatorship, safeguard of justice)
  • Adults unable to give consent
  • Persons deprived of liberty by judicial or administrative decision
  • Persons under psychiatric care as defined by law

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHRU de Nancy

Vandœuvre-lès-Nancy, France, 54500

Actively Recruiting

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Research Team

N

Nicolas GIRERD, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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