Actively Recruiting
Child Cognitive-Affective Resilience Following 13-11 Event : A Pluridisciplinary Study of Intergenerational Transmission of a Traumatic Event
Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2025-10-02
960
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
CARE 13-11 study explores the transmission of trauma within families. Exposure to a traumatic event can have an impact on those directly exposed, but also on their family. This transmission is both biological and behavioral, leading to adaptation that is still poorly understood. CARE 13-11 project offers a unique opportunity to bring together different disciplinary fields, from neuroscience to human and social sciences, to understand this phenomenon. To answer these questions, the study includes directly exposed families with minor children born before the events, as well as families with no exposure to these events (the so-called "control" group).
CONDITIONS
Official Title
Child Cognitive-Affective Resilience Following 13-11 Event : A Pluridisciplinary Study of Intergenerational Transmission of a Traumatic Event
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Minor child born before November 13, 2015
- At least one parent was present at the scene of the attacks or witnessed the event as defined by DSM-5 criteria
- Good command of the French language
- Parents or participant have given written consent for participation
- At least one parent or participant is covered by health insurance or a social security scheme
- For parents: must be parent of included child(ren)
- Parents directly exposed to the attacks or having a spouse directly exposed (declarative basis)
- Uncles/aunts not exposed but with a sibling directly exposed
- Cousins who are minor children born before November 13, 2015, with an aunt or uncle directly exposed
- Control group children with no relative exposed to the attacks
- Control group parents with no exposure to attacks or close relative exposed and no PTSD at inclusion (PCL-5 < 33)
You will not qualify if you...
- Loss of both parents following the November 13 events
- History of severe neurological, mental, or psychopathological disorders such as epilepsy, head trauma with loss of consciousness over one hour, autism spectrum disorder, intellectual disability, or schizophrenia
- Subject to legal protection measures (safeguard of justice, curatorship, guardianship)
- Participation in another research project causing exclusion
- Child's refusal to participate
- Contraindications to MRI for children and parents
- Current pregnancy for women of childbearing age
- Use of psychotropic drugs affecting attention, vigilance, or concentration less than 24 hours before assessments (e.g., sleeping pills, antipsychotics, mood regulators, antiepileptics, antihistamines)
- For parents: history of neurological or neurodevelopmental disorders prior to the attacks except ADHD
- Parent's refusal to participate in research
- Planned pregnancy for women of childbearing age parents undergoing on-site protocol
- Doubt about patient's ability to postpone treatment when using psychotropic drugs as above without medical advice
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Umr-S 1077 Nimh
Caen, France, 14000
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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